Skip to main content

UW Pediatrics

Profile picture for user sihahn


Sihoun Hahn, MD, PhD

Genetic Medicine
Biochemical Genetics Clinic
Associated with Fellowship(s)
Medical Biochemical Genetics Fellowship
Professional Bio

Sihoun Hahn, MD, PhD is a Professor of Pediatrics and Adjunct Professor of Medicine at the University of Washington serving as a Medical Director of Biochemical Genetics program and the Director of the Biochemical Genetics Laboratory.

Dr. Hahn's research has focused on developing a newborn screening method for several genetic conditions in which early detection is critical for effective treatment and disease management including Wilson's disease, a genetic disease leading to copper accumulation in various organs including liver and brain. He developed a robust novel mass-population screening technology using proteotypic peptide immunoaffinity enrichment coupled to selected reaction monitoring (immuno-SRM). Lately, Dr. Hahn’s work has centered on exploring, and validating a state-of-art Immuno-SRM, targeted proteomic analysis of extremely low abundance signature peptide biomarkers in dried blood spots for potential newborn screening for Wilson disease, Cystinosis, lysosomal storage disorders (LSD) and various Primary Immunodeficiencies (PIDD) including X-linked agammaglobulinemia (XLA), Wiskott-Aldrich syndrome (WAS) and Adenosine Deaminase (ADA) deficiency. 

Dr. Hahn serves as a member of medical advisory committee of the Wilson's Disease Association and a member of advisory committee for WA State Newborn Screening. Dr. Hahn hopes to improve clinical practice through integrated laboratory testing, True Translational Research. He remains a great believer in prevention: identifying illness and providing interventions to patients before symptoms appear is always preferable to treating developed disease.