As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to making breakthrough discoveries that help prevent, treat and cure childhood disease. SCRI has more than 350 investigators researching hundreds of diseases and disorders, and over $138 million in federal research funding for the 2021 fiscal year. The research institute is organized into nine centers, each one specializing in areas that include immunotherapy, tissue and immune transplantation, outcomes research, clinical and translational research, and child health and behavior. Researchers in the centers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutchinson Cancer Research Center, and with our health care providers at Seattle Children's Hospital. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.