Immunology Publications
The listings below highlight research and contributions by UW Pediatrics faculty. These listings are not intended as a citation but rather a call-out of UW Pediatrics contributions. For official authorship please click the publication link provided.
October 2024
- Blunting specific T-dependent antibody responses with engineered "decoy" B cells. (PMID: 39192583). Molecular therapy.
UW Peds contributing authors: Carol Miao, David Rawlings, Richard James Immunology
September 2024
- DNA-PK inhibition enhances gene editing efficiency in HSPCs for CRISPR-based treatment of X-linked hyper IgM syndrome. Molecular therapy.
UW Peds contributing authors: David Rawlings Immunology
August 2024
- Human plasma cells engineered to secrete bispecifics drive effective in vivo leukemia killing. (PMID: 38959896). Molecular therapy.
UW Peds contributing authors: David Rawlings, Richard James Immunology - Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans. (PMID: 38780621). The Journal of experimental medicine.
UW Peds contributing authors: Eric Allenspach Immunology
July 2024
- Activated PI3Kδ Specifically Perturbs Mouse Regulatory T Cell Homeostasis and Function Leading to Immune Dysregulation. (PMID: 38829130). Journal of immunology.
UW Peds contributing authors: David Rawlings Immunology
June 2024
- Wiskott-Aldrich syndrome: a study of 577 patients defines the genotype as a biomarker for disease severity and survival (PMID: 38579284). Blood.
UW Peds contributing authors: Hans Ochs Immunology
May 2024
- Multimodal analysis of RNA sequencing data powers discovery of complex trait genetics (PMID: 38798366). bioRxiv.
UW Peds contributing authors: Pejman Mohammadi, Richard James Immunology
April 2024
- Improved multi-ancestry fine-mapping identifies cis-regulatory variants underlying molecular traits and disease risk. (PMID: 38699369). medRxiv.
UW Peds contributing authors: Pejman Mohammadi, Richard James Immunology - A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats. (PMID: 38537634). Cell genomics.
UW Peds contributing authors: Pejman Mohammadi Immunology - Recalibrating differential gene expression by genetic dosage variance prioritizes functionally relevant genes (PMID: 38645217). bioRxiv.
UW Peds contributing authors: Pejman Mohammadi Immunology - BCR signaling is required for posttransplant lymphoproliferative disease in immunodeficient mice receiving human B cells (PMID: 38598616). Science translational medicine.
UW Peds contributing authors: David Rawlings, Richard James Immunology - Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers (PMID: 38513666). Immunity.
UW Peds contributing authors: David Rawlings Immunology - HSPA8 chaperone complex drives chaperone-mediated autophagy regulation in acute promyelocytic leukemia cell differentiation (PMID: 38569476). Pharmacology.
UW Peds contributing authors: Bruce Torbett Immunology
March 2024
- GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes (PMID: 38516892). JCI Insight.
UW Peds contributing authors: David Rawlings Immunology - Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition (PMID: 38518746). Cell chemical biology.
UW Peds contributing authors: Bruce Torbett Immunology - IP6 and PF74 affect HIV-1 Capsid Stability through Modulation of Hexamer-Hexamer Tilt Angle Preference (PMID: 38559213). bioRxiv.
UW Peds contributing authors: Bruce Torbett Immunology
February 2024
- The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner (PMID: 38487540). Frontiers in Immunology.
UW Peds contributing authors: Eric Allenspach, Kathleen J. Millen, David Rawlings Immunology - Immunological signatures unveiled by integrative systems vaccinology characterization of dengue vaccination trials and natural infection. (PMID: 38444851). Frontiers in Immunology.
UW Peds contributing authors: Hans Ochs Immunology
January 2024
- Efficient and sustained FOXP3 locus editing in hematopoietic stem cells as a therapeutic approach for IPEX syndrome (PMID: 38282895). Molecular Therapy, Methods & Clinical Development.
UW Peds contributing authors: David Rawlings Immunology - PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants (PMID: 37769878). Journal of Allergy and Clinical Immunology.
UW Peds contributing authors: Eric Allenspach Immunology
December 2023
- Evaluating the prevalence of inborn errors of immunity in adults with chronic immune thrombocytopenia or Evans syndrome (PMID: 37792884). Blood Adv..
UW Peds contributing authors: Eric Allenspach Immunology - Evaluating the prevalence of inborn errors of immunity in adults with chronic immune thrombocytopenia or Evans syndrome (PMID: 37792884). Blood Advances.
UW Peds contributing authors: Eric Allenspach Immunology
November 2023
- Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition (PMID: 37798411). Nat Neurosci..
UW Peds contributing authors: Pejman Mohammadi Immunology
October 2023
- Neuroimmunology of rabies: New insights into an ancient disease (PMID: 37885152). Journal of Medical Virology.
UW Peds contributing authors: Hans Ochs Immunology - Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation (PMID: 37714151). Immunity.
UW Peds contributing authors: Mridu Acharya Immunology